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Lebeau, Michelle M.
One or more keywords matched the following properties of
Lebeau, Michelle M.
Property
Value
keywords
Preclinical studies using mouse models
keywords
Development of mouse models for human leukemias
One or more keywords matched the following items that are connected to
Lebeau, Michelle M.
Item Type
Name
Concept
Mice, Transgenic
Concept
Mice, Inbred BALB C
Concept
Mice, Inbred C57BL
Concept
Mice, Nude
Concept
Mice, Knockout
Concept
Mice
Concept
Mice, 129 Strain
Concept
Mice, Mutant Strains
Academic Article
Genomic organization and chromosomal localization of the gene TCF15 encoding the early mesodermal basic helix-loop-helix factor bHLH-EC2.
Academic Article
Expression and cytogenetic localization of the human SM22 gene (TAGLN).
Academic Article
Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line.
Academic Article
Chromosomal location and some structural features of human clathrin light-chain genes (CLTA and CLTB).
Academic Article
Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia.
Academic Article
Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.
Academic Article
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
Academic Article
Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc.
Academic Article
ß-Catenin induces T-cell transformation by promoting genomic instability.
Academic Article
Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice.
Academic Article
MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.
Academic Article
Overexpression and knockout of miR-126 both promote leukemogenesis.
Academic Article
Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
Academic Article
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Academic Article
Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Academic Article
Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.
Academic Article
Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model.
Academic Article
Therapy-related myeloid neoplasms: when genetics and environment collide.
Academic Article
DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.
Academic Article
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.
Academic Article
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer.
Academic Article
Dissecting the role of aberrant DNA methylation in human leukaemia.
Search Criteria
mouse
genetics